Structure of PDB 5vpe Chain A Binding Site BS01

Receptor Information
>5vpe Chain A (length=67) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SEEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEI
AELQKEKERLEFVLVAH
Ligand information
Receptor-Ligand Complex Structure
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PDB5vpe Activator Protein-1: redox switch controlling structure and DNA-binding.
Resolution2.053 Å
Binding residue
(original residue number in PDB)
R161 R164 K171 R176
Binding residue
(residue number reindexed from 1)
R10 R13 K20 R25
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function

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Biological Process
External links
PDB RCSB:5vpe, PDBe:5vpe, PDBj:5vpe
PDBsum5vpe
PubMed28981703
UniProtP53539|FOSB_HUMAN Protein FosB (Gene Name=FOSB)

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