Structure of PDB 5vmz Chain A Binding Site BS01

Receptor Information
>5vmz Chain A (length=122) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKV
FPLAQYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGD
SKLYRLHPCRSLQIRQYAYLSD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vmz CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso.
Resolution2.319 Å
Binding residue
(original residue number in PDB)		R501 Y503 V504 C505 S508 R511 Q535 Y536 Q563 F564 R595 Y597 A598
Binding residue
(residue number reindexed from 1)		R21 Y23 V24 C25 S28 R31 Q55 Y56 Q83 F84 R115 Y117 A118
Binding affinityPDBbind-CN: Kd=7.2nM
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5vmz, PDBe:5vmz, PDBj:5vmz
PDBsum5vmz
PubMed29546986
UniProtQ86T24|KAISO_HUMAN Transcriptional regulator Kaiso (Gene Name=ZBTB33)

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