Structure of PDB 5vmv Chain A Binding Site BS01
Receptor Information
>5vmv Chain A (length=116) Species:
9606
(Homo sapiens) [
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DDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKV
FPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGD
SKLYRLHPCRSLQIRQ
Ligand information
>5vmv Chain D (length=18) [
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tgcttctcgcgagaagca
Receptor-Ligand Complex Structure
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PDB
5vmv
CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso.
Resolution
2.313 Å
Binding residue
(original residue number in PDB)
R501 Y503 V504 C505 S508 R511 E535 Q563 R595
Binding residue
(residue number reindexed from 1)
R21 Y23 V24 C25 S28 R31 E55 Q83 R115
Binding affinity
PDBbind-CN
: Kd=0.43nM
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5vmv
,
PDBe:5vmv
,
PDBj:5vmv
PDBsum
5vmv
PubMed
29546986
UniProt
Q86T24
|KAISO_HUMAN Transcriptional regulator Kaiso (Gene Name=ZBTB33)
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