Structure of PDB 5vmu Chain A Binding Site BS01
Receptor Information
>5vmu Chain A (length=121) Species:
9606
(Homo sapiens) [
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DDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKV
FPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGD
SKLYRLHPCRSLQIRQYAYLS
Ligand information
>5vmu Chain D (length=18) [
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tgcttcccgcgaataacg
Receptor-Ligand Complex Structure
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PDB
5vmu
CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso.
Resolution
2.346 Å
Binding residue
(original residue number in PDB)
Y503 V504 S508 R511 E535 Y536 Q563 F564 Y597 A598
Binding residue
(residue number reindexed from 1)
Y23 V24 S28 R31 E55 Y56 Q83 F84 Y117 A118
Binding affinity
PDBbind-CN
: Kd=0.2nM
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5vmu
,
PDBe:5vmu
,
PDBj:5vmu
PDBsum
5vmu
PubMed
29546986
UniProt
Q86T24
|KAISO_HUMAN Transcriptional regulator Kaiso (Gene Name=ZBTB33)
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