Structure of PDB 5vgd Chain A Binding Site BS01

Receptor Information
>5vgd Chain A (length=273) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHSMRYFYTAVSRPGRGEPRFIAVGYVDDTQFVQFDSDAASPRGEPRAPW
VEQEGPEYWDRETQKYKRQAQTDRVNLRKLRGYYNQSEAGSHTLQRMYGC
DLGPDGRLLRGYNQFAYDGKDYIALNEDLRSWTAADKAAQITQRKWEAAR
EAEQRRAYLEGTCVEWLRRYLENGKKTLQRAEHPKTHVTHHPVSDHEATL
RCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPS
GEEQRYTCHVQHEGLPEPLTLRW
Ligand information
>5vgd Chain C (length=9) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SAEPVPLQL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vgd Structural and regulatory diversity shape HLA-C protein expression levels.
Resolution2.32 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 R69 Q70 T73 N77 K80 L81 Y84 R97 Y99 F116 T143 K146 W147 R156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 E62 K65 R68 Q69 T72 N76 K79 L80 Y83 R96 Y98 F115 T142 K145 W146 R155 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5vgd, PDBe:5vgd, PDBj:5vgd
PDBsum5vgd
PubMed28649982
UniProtP10321|HLAC_HUMAN HLA class I histocompatibility antigen, C alpha chain (Gene Name=HLA-C)

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