Structure of PDB 5vfg Chain A Binding Site BS01

Receptor Information
>5vfg Chain A (length=151) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKLGDISFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG
KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKN
DAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAVK
K
Ligand information
Ligand IDPB
InChIInChI=1S/Pb/q+2
InChIKeyRVPVRDXYQKGNMQ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.370[Pb++]
valence
OpenEye OEToolkits 1.7.2[Pb+2]
FormulaPb
NameLEAD (II) ION
ChEMBL
DrugBank
ZINC
PDB chain5vfg Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vfg High affinity interactions of Pb2+with synaptotagmin I.
Resolution1.82 Å
Binding residue
(original residue number in PDB)		D303 D309 D363 Y364 D365
Binding residue
(residue number reindexed from 1)		D33 D39 D93 Y94 D95
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:5vfg, PDBe:5vfg, PDBj:5vfg
PDBsum5vfg
PubMed30063057
UniProtP46096|SYT1_MOUSE Synaptotagmin-1 (Gene Name=Syt1)

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