Structure of PDB 5vff Chain A Binding Site BS01

Receptor Information
>5vff Chain A (length=149) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKLGDISFSLRYVPTAGKLTVVILEAKNLKKMDVLSDPYVKIHLMQNGKR
LKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDA
IGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAVKK
Ligand information
Ligand IDPB
InChIInChI=1S/Pb/q+2
InChIKeyRVPVRDXYQKGNMQ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.370[Pb++]
valence
OpenEye OEToolkits 1.7.2[Pb+2]
FormulaPb
NameLEAD (II) ION
ChEMBL
DrugBank
ZINC
PDB chain5vff Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vff High affinity interactions of Pb2+with synaptotagmin I.
Resolution1.413 Å
Binding residue
(original residue number in PDB)		D309 D363 Y364
Binding residue
(residue number reindexed from 1)		D37 D91 Y92
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:5vff, PDBe:5vff, PDBj:5vff
PDBsum5vff
PubMed30063057
UniProtP46096|SYT1_MOUSE Synaptotagmin-1 (Gene Name=Syt1)

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