Structure of PDB 5vfe Chain A Binding Site BS01

Receptor Information
>5vfe Chain A (length=125) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKK
KKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDII
GEFKVPMNTVDFGHVTEEWRDLQSA
Ligand information
Ligand IDPB
InChIInChI=1S/Pb/q+2
InChIKeyRVPVRDXYQKGNMQ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.370[Pb++]
valence
OpenEye OEToolkits 1.7.2[Pb+2]
FormulaPb
NameLEAD (II) ION
ChEMBL
DrugBank
ZINC
PDB chain5vfe Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vfe High affinity interactions of Pb2+with synaptotagmin I.
Resolution1.38 Å
Binding residue
(original residue number in PDB)		D172 D178 D230 F231
Binding residue
(residue number reindexed from 1)		D32 D38 D90 F91
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:5vfe, PDBe:5vfe, PDBj:5vfe
PDBsum5vfe
PubMed30063057
UniProtP46096|SYT1_MOUSE Synaptotagmin-1 (Gene Name=Syt1)

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