Structure of PDB 5vc8 Chain A Binding Site BS01
Receptor Information
>5vc8 Chain A (length=125) Species:
9606
(Homo sapiens) [
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HLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKARQYHVQFFGDA
PERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRA
QWEMGIVQAEEAASMSVEERKAKFT
Ligand information
>5vc8 Chain W (length=12) [
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gagatcgatctc
Receptor-Ligand Complex Structure
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PDB
5vc8
Histone and DNA binding ability studies of the NSD subfamily of PWWP domains.
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
K304 A305
Binding residue
(residue number reindexed from 1)
K84 A85
Enzymatic activity
Enzyme Commision number
2.1.1.357
: [histone H3]-lysine(36) N-dimethyltransferase.
External links
PDB
RCSB:5vc8
,
PDBe:5vc8
,
PDBj:5vc8
PDBsum
5vc8
PubMed
34271259
UniProt
O96028
|NSD2_HUMAN Histone-lysine N-methyltransferase NSD2 (Gene Name=NSD2)
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