Structure of PDB 5vay Chain A Binding Site BS01

Receptor Information
>5vay Chain A (length=151) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSMAHAGRTGYDNREIVMKYIHYKLSQRGYEWDASEVVHLTLRQAGDDFS
RRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGG
VMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPS
M
Ligand information
>5vay Chain E (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DMENLSRRLKVTGDLFDIMSG
Receptor-Ligand Complex Structure
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PDB5vay Bcl-2 complex with Beclin 1 pT108 BH3 domain
Resolution1.804 Å
Binding residue
(original residue number in PDB)		D103 F104 R107 Y108 F112 M115 R129 V133 E136 L137 D140 N143 W144 G145 R146 F153 Y202
Binding residue
(residue number reindexed from 1)		D48 F49 R52 Y53 F57 M60 R74 V78 E81 L82 D85 N88 W89 G90 R91 F98 Y147
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:5vay, PDBe:5vay, PDBj:5vay
PDBsum5vay
PubMed
UniProtP10415|BCL2_HUMAN Apoptosis regulator Bcl-2 (Gene Name=BCL2);
Q07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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