Structure of PDB 5vau Chain A Binding Site BS01

Receptor Information
>5vau Chain A (length=151) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSMAHAGRTGYDNREIVMKYIHYKLSQRGYEWDASEVVHLTLRQAGDDFS
RRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGG
VMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPS
M
Ligand information
>5vau Chain E (length=20) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MENLSRRLKVTGDLFDIMSG
Receptor-Ligand Complex Structure
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PDB5vau Bcl-2 complex with Beclin 1 BH3 domain
Resolution1.754 Å
Binding residue
(original residue number in PDB)		F104 R107 Y108 F112 M115 R129 E136 L137 D140 N143 G145 R146 F153 Y202
Binding residue
(residue number reindexed from 1)		F49 R52 Y53 F57 M60 R74 E81 L82 D85 N88 G90 R91 F98 Y147
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

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Biological Process
External links
PDB RCSB:5vau, PDBe:5vau, PDBj:5vau
PDBsum5vau
PubMed
UniProtP10415|BCL2_HUMAN Apoptosis regulator Bcl-2 (Gene Name=BCL2)

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