Structure of PDB 5vap Chain A Binding Site BS01

Receptor Information
>5vap Chain A (length=111) Species: 1570291 (Ebola virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ITLLTLIKTAEHWARQDIRTIEDSKLRALLTLCAVMTRKFSKSQLSLLCE
THLRREGLGQDQAEPVLEVYQRLHSDKGGSFEAALWQQWDRQSLIMFITA
FLNIALQLPCE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vap Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		E197 L199 Q203 E209 R213 S221 F222 A225 Q229 W230 S234
Binding residue
(residue number reindexed from 1)		E56 L58 Q62 E68 R72 S80 F81 A84 Q88 W89 S93
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5vap, PDBe:5vap, PDBj:5vap
PDBsum5vap
PubMed28593988
UniProtQ77DJ5|VP30_EBOZ5 Transcriptional activator VP30 (Gene Name=VP30)

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