Structure of PDB 5va4 Chain A Binding Site BS01

Receptor Information
>5va4 Chain A (length=123) Species: 9505,262724 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DHCAHHGEKLVLFCQQDGNVICWLCERSQEHRGHQTFLVEEVAQKYREKL
QVALEMMRQKQKDAETECNQVAKRVALIARGKACGEQTQSVRVLISDLEH
RLQGSVMELLQGVDGVIKRIEKV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5va4 Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5va4 General Model for Retroviral Capsid Pattern Recognition by TRIM5 Proteins.
Resolution2.306 Å
Binding residue
(original residue number in PDB)		C107 D110 H124 H127
Binding residue
(residue number reindexed from 1)		C14 D17 H31 H34
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) K220
Catalytic site (residue number reindexed from 1) K118
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
6.1.1.11: serine--tRNA ligase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5va4, PDBe:5va4, PDBj:5va4
PDBsum5va4
PubMed29187540
UniProtP34945|SYS_THET2 Serine--tRNA ligase (Gene Name=serS);
Q68KK2

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