Structure of PDB 5v5m Chain A Binding Site BS01

Receptor Information
>5v5m Chain A (length=278) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAP
WIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYG
CDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEPHH
Ligand information
>5v5m Chain E (length=10) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TSTLQEQIGW
Receptor-Ligand Complex Structure
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PDB5v5m Crystal structure of HLA-B*5801 with a TW10 HIV Gag epitope reveals a novel mode of peptide presentation.
Resolution2.878 Å
Binding residue
(original residue number in PDB)
Y7 E63 N66 M67 A69 S70 T73 N77 I80 Y84 I95 Y99 S116 Y123 T143 W147 V152 Q155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 N66 M67 A69 S70 T73 N77 I80 Y84 I95 Y99 S116 Y123 T143 W147 V152 Q155 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5v5m, PDBe:5v5m, PDBj:5v5m
PDBsum5v5m
PubMed28552904
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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