Structure of PDB 5v1q Chain A Binding Site BS01

Receptor Information
>5v1q Chain A (length=428) Species: 1307 (Streptococcus suis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RTISEDILFRLEKFGGILINKTNFERIELDETEAFFLYLVQNHGIEIATS
FFKKEIEMGKLERALSLNIYSDNNPYETLQNARKHVAKLKKHNILSFPLE
LVIYPSMYCDLKCGFCFLANREAKPAKDWERILRQAKDNGVLSVSILGGE
PTRYFDIDNLLIACEELKIKTTITTNAQLIKKSTVEILAKSKYITPVLSL
QTLDSKLNFELMGVRPDRQIKLAKYFNEVGKKCRINAVYTKQSYEQIIEL
VDFCIENKIDRFSVANYSEVTGYTKIKKKYDLADLRRLNEYVTDYITQRE
ANLNFATEGCHLFTAYPELINNSIEFSEFDEMYYGCRAKYTKMEIMSNGD
ILPCIAFLGVNQTKQNAFEKDLLDVWYDDPLYGGIRSFRTKNSKCLSCGL
LKICEGGCYVNLIKEKSPEYFRDSVCQL
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain5v1q Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5v1q Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
C117 L119 K120 C121 C124 N187
Binding residue
(residue number reindexed from 1)
C109 L111 K112 C113 C116 N176
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding

View graph for
Molecular Function
External links
PDB RCSB:5v1q, PDBe:5v1q, PDBj:5v1q
PDBsum5v1q
PubMed28893989
UniProtA0A0Z8EWX1

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