Structure of PDB 5uy4 Chain A Binding Site BS01

Receptor Information
>5uy4 Chain A (length=271) Species: 632 (Yersinia pestis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKKFKVVTTFTIIQDIAQNIAGDVAVVESITKPGAEIHDYQPTPRDIVKA
QSADLILWNGMNLERWFEKFFESIKDVPSAVVTAGITPLPIREGPYSGIA
NPHAWMSPSNALIYIENIRKALVEHDPAHAETYNRNAQAYAEKIKALDAP
LRERLSRIPAEQRWLVTSEGAFSYLAKDYGFKEVYLWPINAEQQGIPQQV
RHVIDIIRENKIPVVFSESTISDKPAKQVSKETGAQYGGVLYVDSLSGEK
GPVPTYISLINMTVDTIAKGF
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain5uy4 Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5uy4 Crystal structure of Yersinia pestis virulence factor YfeA reveals two polyspecific metal-binding sites.
Resolution1.915 Å
Binding residue
(original residue number in PDB)		H76 H141 E207 D282
Binding residue
(residue number reindexed from 1)		H38 H103 E169 D244
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0007155 cell adhesion
GO:0030001 metal ion transport

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5uy4, PDBe:5uy4, PDBj:5uy4
PDBsum5uy4
PubMed28695856
UniProtQ56952|YFEA_YERPE Iron-binding protein YfeA (Gene Name=yfeA)

[Back to BioLiP]