Structure of PDB 5use Chain A Binding Site BS01

Receptor Information
>5use Chain A (length=132) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EIIWESLSVDVGSQGNPGIVEYKGVDTKTGEVLFEREPIPIGTNNMGEFL
AIVHGLRYLKERNSRKPIYSNSQTAIKWVKDKKAKSTLVRNEETALIWKL
VDEAEEWLNTHTYETPILKWQTDKWGEIKADY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5use Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate
Resolution1.73 Å
Binding residue
(original residue number in PDB)		N105 E109 N132 Q134 K180 T183
Binding residue
(residue number reindexed from 1)		N44 E48 N71 Q73 K119 T122
Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:5use, PDBe:5use, PDBj:5use
PDBsum5use
PubMed
UniProtQ9KEI9|RNH1_HALH5 Ribonuclease H (Gene Name=rnhA)

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