Structure of PDB 5un8 Chain A Binding Site BS01
Receptor Information
>5un8 Chain A (length=424) Species:
9606
(Homo sapiens) [
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HFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWR
EMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKL
DQVSQFGCRSFALLFDNIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGE
PETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKE
IPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLK
GVLTNPNCEFEANYVAIHTLATWYKYSPQMALKLALTEWLQEFGVPHQYS
VTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVIEEWRSRAAK
FEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGC
RSWAFRGGLAGEFQRLLPIDGAND
Ligand information
>5un8 Chain E (length=7) Species:
9606
(Homo sapiens) [
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WVDSTPP
Receptor-Ligand Complex Structure
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PDB
5un8
Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.
Resolution
2.13 Å
Binding residue
(original residue number in PDB)
N175 I176 D177 Y219 F223 V254
Binding residue
(residue number reindexed from 1)
N117 I118 D119 Y161 F165 V196
Enzymatic activity
Enzyme Commision number
3.2.1.169
: protein O-GlcNAcase.
External links
PDB
RCSB:5un8
,
PDBe:5un8
,
PDBj:5un8
PDBsum
5un8
PubMed
28319083
UniProt
O60502
|OGA_HUMAN Protein O-GlcNAcase (Gene Name=OGA)
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