Structure of PDB 5uly Chain A Binding Site BS01

Receptor Information
>5uly Chain A (length=224) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TFKHESYYATVNELTPVGTTIFTGFSGDNGATQIEYVIQYNPDDPTSNDT
FEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANTTTTTLTVDVLDGDDLGP
MFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNI
QPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDL
VIKAEQDNGHPLPAFAGLHIEILD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5uly Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5uly Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception.
Resolution2.64 Å
Binding residue
(original residue number in PDB)		E137 D236 G237 D239 D289
Binding residue
(residue number reindexed from 1)		E13 D94 G95 D97 D147
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5uly, PDBe:5uly, PDBj:5uly
PDBsum5uly
PubMed32963095
UniProtQ96QU1|PCD15_HUMAN Protocadherin-15 (Gene Name=PCDH15)

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