Structure of PDB 5ug7 Chain A Binding Site BS01

Receptor Information
>5ug7 Chain A (length=126) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QRGLAHLVVSNFRAEHLAGDADTATDAYLKVFFGGQEFRTGVVWNNNNPR
WTDKMDFENVLLSTGGPLRVQVWDADAGADDDLLGSCDRSPHSGFHEVTC
ELNHGRVKFSYHAKCLPHLTGGTCLE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5ug7 Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ug7 Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D429 T432 A433 D435 N454
Binding residue
(residue number reindexed from 1)		D20 T23 A24 D26 N45
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5ug7, PDBe:5ug7, PDBj:5ug7
PDBsum5ug7
PubMed29416110
UniProtP10820|PERF_MOUSE Perforin-1 (Gene Name=Prf1)

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