Structure of PDB 5tzq Chain A Binding Site BS01

Receptor Information
>5tzq Chain A (length=132) Species: 928301 (Fowlpox virus strain NVSL) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKDETYYIALNMIQNYIIEYNTNKPRKSFVIDSISYDVLKAACKSVIKTN
YNEFDIIISRNIDFNVIVTQVLEDKINWGRIITIIAFCAYYSKKVPQYYD
GIISEAITDAILSKYRSWFIDQDYWNGIRIYK
Ligand information
>5tzq Chain D (length=22) Species: 9031 (Gallus gallus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ARTEVQIARKLQCIADQFHRLH
Receptor-Ligand Complex Structure
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PDB5tzq Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039.
Resolution1.65 Å
Binding residue
(original residue number in PDB)
V51 N55 F59 I67 V71 I72 Q75 V76 G84 R85 T88 Y141
Binding residue
(residue number reindexed from 1)
V46 N50 F54 I62 V66 I67 Q70 V71 G79 R80 T83 Y131
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:5tzq, PDBe:5tzq, PDBj:5tzq
PDBsum5tzq
PubMed28411240
UniProtQ9J5G4|ARBH_FOWPN Apoptosis regulator Bcl-2 homolog (Gene Name=FPV039)

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