Structure of PDB 5txs Chain A Binding Site BS01

Receptor Information
>5txs Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAP
WIEQEGPEYWDRETQISKTNTQTYRESLRNLRGYYNQSEAGSHTLQRMYG
CDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
REAEQWRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5txs A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.
Resolution1.697 Å
Binding residue
(original residue number in PDB)
Y7 Y9 M45 R62 E63 T69 N70 T73 E76 S77 Y84 R97 Y99 S116 K146 W147 E152 Q155 W156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 Y9 M45 R62 E63 T69 N70 T73 E76 S77 Y84 R97 Y99 S116 K146 W147 E152 Q155 W156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5txs, PDBe:5txs, PDBj:5txs
PDBsum5txs
PubMed29441070
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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