Structure of PDB 5tsa Chain A Binding Site BS01

Receptor Information
>5tsa Chain A (length=233) Species: 257310 (Bordetella bronchiseptica RB50) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NRVHVGYAVLGGAAGFAATALGALMALGLRAISARTQDAMLGFAAGMMLA
ASAFSLILPGLDAAGTIVGPGPAAAAVVALGLGLGVLLMLGLDYFTVNRV
WLFVLTIILHNLPEGMAIGVSFATGDLRIGLPLTSAIAIQDVPEGLAVAL
ALRAVGLPIGRAVLVAVASGLMEPLGALVGVGISSGFALAYPISMGLAAG
AMIFVVSHEVHETTATVGLMAGFALMMFLDTAL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5tsa Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5tsa Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		E181 Q207 E211
Binding residue
(residue number reindexed from 1)		E114 Q140 E144
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046873 metal ion transmembrane transporter activity
Biological Process
GO:0006829 zinc ion transport
GO:0030001 metal ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5tsa, PDBe:5tsa, PDBj:5tsa
PDBsum5tsa
PubMed28875161
UniProtA0A0H3LM39|ZIP_BORBR Zinc transporter ZIPB (Gene Name=BB2405)

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