Structure of PDB 5trz Chain A Binding Site BS01

Receptor Information
>5trz Chain A (length=275) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRAPW
MEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMFGC
DVGSDWRLLRGYHQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQAG
DAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDVTL
RCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVVPL
GKEQNYTCHVHHKGLPEPLTLRWKP
Ligand information
>5trz Chain P (length=9) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
YQSGLSIVM
Receptor-Ligand Complex Structure
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PDB5trz MHC-restricted Ag85B-specific CD8+T cells are enhanced by recombinant BCG prime and DNA boost immunization in mice.
Resolution2.247 Å
Binding residue
(original residue number in PDB)
Y7 V9 F45 Q63 R66 S69 D70 W73 S77 T80 Y84 R97 I142 T143 K146 W147 D152 Y155 Y156 Y159
Binding residue
(residue number reindexed from 1)
Y6 V8 F44 Q62 R65 S68 D69 W72 S76 T79 Y83 R96 I141 T142 K145 W146 D151 Y154 Y155 Y158
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5trz, PDBe:5trz, PDBj:5trz
PDBsum5trz
PubMed31135967
UniProtP01902|HA1D_MOUSE H-2 class I histocompatibility antigen, K-D alpha chain (Gene Name=H2-K1)

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