Structure of PDB 5tnc Chain A Binding Site BS01

Receptor Information
>5tnc Chain A (length=161) Species: 9103 (Meleagris gallopavo) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMTDQQAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQ
NPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELEDC
FRIFDKNADGFIDIEELGEILRATGEHVTEEDIEDLMKDSDKNNDGRIDF
DEFLKMMEGVQ
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5tnc Chain A Residue 163 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5tnc Refined crystal structure of troponin C from turkey skeletal muscle at 2.0 A resolution.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		D106 N108 D110 F112 E117
Binding residue
(residue number reindexed from 1)		D105 N107 D109 F111 E116
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) V45
Catalytic site (residue number reindexed from 1) V44
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0046872 metal ion binding
Cellular Component
GO:0016460 myosin II complex

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:5tnc, PDBe:5tnc, PDBj:5tnc
PDBsum5tnc
PubMed3210231
UniProtP10246|TNNC2_MELGA Troponin C, skeletal muscle (Gene Name=TNNC2)

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