Structure of PDB 5tn8 Chain A Binding Site BS01
Receptor Information
>5tn8 Chain A (length=228) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEPFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNK
GMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5tn8 Chain C (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tn8
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.652 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I49 K53 L63 V67 D218 L219 E222
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tn8
,
PDBe:5tn8
,
PDBj:5tn8
PDBsum
5tn8
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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