Structure of PDB 5tn3 Chain A Binding Site BS01
Receptor Information
>5tn3 Chain A (length=238) Species:
9606
(Homo sapiens) [
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KNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADR
ELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKL
LFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSII
LLNSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLI
LSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5tn3 Chain C (length=11) Species:
9606
(Homo sapiens) [
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KHKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tn3
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.543 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 L379 E380 L539 E542
Binding residue
(residue number reindexed from 1)
I56 K60 V74 L77 E78 L229 E232
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tn3
,
PDBe:5tn3
,
PDBj:5tn3
PDBsum
5tn3
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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