Structure of PDB 5tn1 Chain A Binding Site BS01

Receptor Information
>5tn1 Chain A (length=245) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKKNSLALSLTADQMVSALLDAEPPILYSEYRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQR
LAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5tn1 Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution2.055 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I55 K59 L69 V73 D235 L236 E239
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5tn1, PDBe:5tn1, PDBj:5tn1
PDBsum5tn1
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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