Structure of PDB 5tmz Chain A Binding Site BS01
Receptor Information
>5tmz Chain A (length=236) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTFEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5tmz Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tmz
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.207 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 E542
Binding residue
(residue number reindexed from 1)
I55 K59 L69 V73 E77 E230
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tmz
,
PDBe:5tmz
,
PDBj:5tmz
PDBsum
5tmz
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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