Structure of PDB 5tmw Chain A Binding Site BS01
Receptor Information
>5tmw Chain A (length=240) Species:
9606
(Homo sapiens) [
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KKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLAD
RELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK
LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSI
ILLNSGVYTFLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL
LILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5tmw Chain C (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tmw
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.286 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 D538 E542
Binding residue
(residue number reindexed from 1)
I57 K61 L71 V75 D230 E234
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tmw
,
PDBe:5tmw
,
PDBj:5tmw
PDBsum
5tmw
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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