Structure of PDB 5tms Chain A Binding Site BS01
Receptor Information
>5tms Chain A (length=234) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI
RHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5tms Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tms
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.24 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 V72 E76 D224 L225 E228
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tms
,
PDBe:5tms
,
PDBj:5tms
PDBsum
5tms
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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