Structure of PDB 5tmr Chain A Binding Site BS01
Receptor Information
>5tmr Chain A (length=242) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTFTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQ
LLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5tmr Chain C (length=10) Species:
9606
(Homo sapiens) [
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KILHRLLQDS
Receptor-Ligand Complex Structure
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PDB
5tmr
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.296 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 L379 D538 L539 E542 M543
Binding residue
(residue number reindexed from 1)
I55 K59 L69 V73 L76 D232 L233 E236 M237
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tmr
,
PDBe:5tmr
,
PDBj:5tmr
PDBsum
5tmr
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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