Structure of PDB 5tmo Chain A Binding Site BS01
Receptor Information
>5tmo Chain A (length=235) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5tmo Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tmo
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.172 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I55 K59 V73 E77 D225 L226 E229
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tmo
,
PDBe:5tmo
,
PDBj:5tmo
PDBsum
5tmo
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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