Structure of PDB 5tm9 Chain A Binding Site BS01

Receptor Information
>5tm9 Chain A (length=215) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5tm9 Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5tm9, PDBe:5tm9, PDBj:5tm9
PDBsum5tm9
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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