Structure of PDB 5tm6 Chain A Binding Site BS01
Receptor Information
>5tm6 Chain A (length=234) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYDPPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFLKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI
RHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5tm6 Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tm6
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.542 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 L539 E542
Binding residue
(residue number reindexed from 1)
I53 K57 L67 V71 E75 L225 E228
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tm6
,
PDBe:5tm6
,
PDBj:5tm6
PDBsum
5tm6
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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