Structure of PDB 5tm4 Chain A Binding Site BS01
Receptor Information
>5tm4 Chain A (length=228) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMSDLLLEMLDAHR
Ligand information
>5tm4 Chain C (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tm4
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.25 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 D218 L219 E222
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tm4
,
PDBe:5tm4
,
PDBj:5tm4
PDBsum
5tm4
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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