Structure of PDB 5tm3 Chain A Binding Site BS01
Receptor Information
>5tm3 Chain A (length=231) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
SLALSLTADQMVSALLDAEPPILYSEYDPFSEASMMGLLTNLADRELVHM
INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPN
LLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSG
VYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHM
SNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5tm3 Chain C (length=9) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
KILHRLLQD
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
5tm3
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.194 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 E380 D538 E542
Binding residue
(residue number reindexed from 1)
I51 K55 V69 E73 D221 E225
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tm3
,
PDBe:5tm3
,
PDBj:5tm3
PDBsum
5tm3
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
[
Back to BioLiP
]
