Structure of PDB 5tm2 Chain A Binding Site BS01
Receptor Information
>5tm2 Chain A (length=217) Species:
9606
(Homo sapiens) [
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LALSLTADQMVSALLDAEPPILYSEFSEASMMGLLTNLADRELVHMINWA
KRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLD
RNQGKCMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTKDHI
HRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHL
YSMKCPLSDLLLEMLDA
Ligand information
>5tm2 Chain C (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tm2
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.603 Å
Binding residue
(original residue number in PDB)
I358 V376 D538 E542
Binding residue
(residue number reindexed from 1)
I47 V65 D209 E213
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tm2
,
PDBe:5tm2
,
PDBj:5tm2
PDBsum
5tm2
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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