Structure of PDB 5tlu Chain A Binding Site BS01
Receptor Information
>5tlu Chain A (length=229) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYPFSEASMMGLLTNLADRELVHMI
NWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNL
LLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGV
YTKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSN
KGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5tlu Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tlu
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.223 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I50 K54 V68 E72 D219 L220 E223
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tlu
,
PDBe:5tlu
,
PDBj:5tlu
PDBsum
5tlu
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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