Structure of PDB 5tlt Chain A Binding Site BS01

Receptor Information
>5tlt Chain A (length=234) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADR
ELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKL
LFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSII
LLNSGVYKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI
RHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5tlt Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution1.903 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 E542
Binding residue
(residue number reindexed from 1)
I56 K60 L70 V74 E78 E228
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5tlt, PDBe:5tlt, PDBj:5tlt
PDBsum5tlt
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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