Structure of PDB 5tlo Chain A Binding Site BS01
Receptor Information
>5tlo Chain A (length=229) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
LALSLTADQMVSALLDAEPPILYSEYDRPFSEASMMGLLTNLADRELVHM
INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPN
LLLDRNEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFK
SLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHM
SNKGMEHLYSMKNVVPLSDLLLEMLDAHR
Ligand information
>5tlo Chain C (length=9) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
KILHRLLQD
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
5tlo
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.28 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 L379 E380 D538 E542
Binding residue
(residue number reindexed from 1)
I51 K55 V69 L72 E73 D219 E223
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tlo
,
PDBe:5tlo
,
PDBj:5tlo
PDBsum
5tlo
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
[
Back to BioLiP
]
