Structure of PDB 5tlm Chain A Binding Site BS01

Receptor Information
>5tlm Chain A (length=226) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRH
MSNKGMEHLYSMKLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5tlm Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution2.497 Å
Binding residue
(original residue number in PDB)
I358 K362 V376
Binding residue
(residue number reindexed from 1)
I53 K57 V71
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5tlm, PDBe:5tlm, PDBj:5tlm
PDBsum5tlm
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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