Structure of PDB 5tll Chain A Binding Site BS01
Receptor Information
>5tll Chain A (length=235) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5tll Chain C (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5tll
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.423 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 L379 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 L75 D225 L226 E229
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5tll
,
PDBe:5tll
,
PDBj:5tll
PDBsum
5tll
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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