Structure of PDB 5tgh Chain A Binding Site BS01

Receptor Information
>5tgh Chain A (length=142) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLQIDIPDALSERDKVKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTL
IETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELE
AEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQP
Ligand information
>5tgh Chain B (length=21) Species: 813 (Chlamydia trachomatis) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PAVQFFKGKNGSADQVILVTQ
Receptor-Ligand Complex Structure
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PDB5tgh Structural basis for the hijacking of endosomal sorting nexin proteins byChlamydia trachomatis.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		I35 P36 D37 A38 L39 S40 E41 R42 E129 Y132 L133 F136 V140 E144
Binding residue
(residue number reindexed from 1)		I6 P7 D8 A9 L10 S11 E12 R13 E100 Y103 L104 F107 V111 E115
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0035091 phosphatidylinositol binding

View graph for
Molecular Function
External links
PDB RCSB:5tgh, PDBe:5tgh, PDBj:5tgh
PDBsum5tgh
PubMed28226239
UniProtQ9Y5X3|SNX5_HUMAN Sorting nexin-5 (Gene Name=SNX5)

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