Structure of PDB 5tda Chain A Binding Site BS01

Receptor Information
>5tda Chain A (length=71) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHRDHRYRMTTSGGG
GFCDCGDTEAWKEGPYCQKHE
Ligand information
Receptor-Ligand Complex Structure
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PDB5tda Bound Waters Mediate Binding of Diverse Substrates to a Ubiquitin Ligase.
Resolution0.79 Å
Binding residue
(original residue number in PDB)		T120 V122 G147 F148 D150 D153
Binding residue
(residue number reindexed from 1)		T24 V26 G51 F52 D54 D57
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:5tda, PDBe:5tda, PDBj:5tda
PDBsum5tda
PubMed28392261
UniProtQ8IWV8|UBR2_HUMAN E3 ubiquitin-protein ligase UBR2 (Gene Name=UBR2)

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