Structure of PDB 5tcv Chain A Binding Site BS01

Receptor Information
>5tcv Chain A (length=299) Species: 4102 (Petunia x hybrida) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NFPIISLDKVNGVERAATMEMIKDACENWGFFELVNHGIPREVMDTVEKM
TKGHYKKCMEQRFKELVASKALEGVQAEVTDMDWESTFFLKHLPISNISE
VPDLDEEYREVMRDFAKRLEKLAEELLDLLCENLGLEKGYLKNAFYGSKG
PNFGTKVSNYPPCPKPDLIKGLRAHTDAGGIILLFQDDKVSGLQLLKDGQ
WIDVPPMRHSIVVNLGDQLEVITNGKYKSVMHRVIAQKDGARMSLASFYN
PGSDAVIYPAPALVEKQVYPKFVFDDYMKLYAGLKFQAKEPRFEAMKAM
Ligand information
Ligand ID1AC
InChIInChI=1S/C4H7NO2/c5-4(1-2-4)3(6)7/h1-2,5H2,(H,6,7)
InChIKeyPAJPWUMXBYXFCZ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341NC1(CC1)C(O)=O
OpenEye OEToolkits 1.5.0C1CC1(C(=O)O)N
ACDLabs 10.04O=C(O)C1(N)CC1
FormulaC4 H7 N O2
Name1-AMINOCYCLOPROPANECARBOXYLIC ACID
ChEMBLCHEMBL265325
DrugBankDB02085
ZINCZINC000000895536
PDB chain5tcv Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5tcv ACC oxidase complex with substrate 1-aminocyclopropane-1-carboxylic acid
Resolution2.6 Å
Binding residue
(original residue number in PDB)		H177 D179 L195 H234
Binding residue
(residue number reindexed from 1)		H175 D177 L193 H232
Annotation score5
Enzymatic activity
Catalytic site (original residue number in PDB) K158 H177 D179 H234
Catalytic site (residue number reindexed from 1) K156 H175 D177 H232
Enzyme Commision number 1.14.17.4: aminocyclopropanecarboxylate oxidase.
Gene Ontology
Molecular Function
GO:0009815 1-aminocyclopropane-1-carboxylate oxidase activity
GO:0016491 oxidoreductase activity
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0031418 L-ascorbic acid binding
GO:0046872 metal ion binding
Biological Process
GO:0002238 response to molecule of fungal origin
GO:0009693 ethylene biosynthetic process
GO:0009805 coumarin biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5tcv, PDBe:5tcv, PDBj:5tcv
PDBsum5tcv
PubMed
UniProtQ08506|ACCO1_PETHY 1-aminocyclopropane-1-carboxylate oxidase 1 (Gene Name=ACO1)

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