Structure of PDB 5t7g Chain A Binding Site BS01

Receptor Information

>5t7g Chain A (length=273) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SHSLRYFVTAVSRPGFGEPRYMEVGYVDNTEFVRFDSDAENPRYEPRARW
IEQEGPEYWERETRRAKGNEQSFRVDLRTALRYYNQSAGGSHTLQWMAGC
DVESDGRLLRGYWQFAYDGCDYIALNEDLKTWTAADMAAQITRRKWEQAG
AAERDRAYLEGECVEWLRRYLKNGNATLLRTDPPKAHVTHHRRPEGDVTL
RCWALGFYPADITLTWQLNGEELTQEMELVETRPAGDGTFQKWASVVVPL
GKEQKYTCHVEHEGLPEPLTLRW

Ligand information

>5t7g Chain P (length=9) Species: 11696 (HIV-1 M:B_MN) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

IGPGRAFYT

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5t7g Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity.
Resolution	1.961 Å
Binding residue (original residue number in PDB)	Y7 Y59 E63 R66 N70 F74 V76 D77 Y84 W97 W114 T143 K146 W147 A150 A152 R155 Y159 W167 Y171
Binding residue (residue number reindexed from 1)	Y6 Y58 E62 R65 N69 F73 V75 D76 Y83 W96 W113 T142 K145 W146 A149 A151 R154 Y158 W166 Y170

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:5t7g, PDBe:5t7g, PDBj:5t7g
PDBsum	5t7g
PubMed	29374075
UniProt	P01900\|HA12_MOUSE H-2 class I histocompatibility antigen, D-D alpha chain (Gene Name=H2-D1)

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