Structure of PDB 5t70 Chain A Binding Site BS01
Receptor Information
>5t70 Chain A (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAP
WIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYG
CDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>5t70 Chain C (length=10) Species:
32630
(synthetic construct) [
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TSNLQEQIGW
Receptor-Ligand Complex Structure
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PDB
5t70
MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
Y7 E63 N66 S70 T73 N77 I80 Y84 I95 Y99 Y123 T143 K146 W147 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 N66 S70 T73 N77 I80 Y84 I95 Y99 Y123 T143 K146 W147 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5t70
,
PDBe:5t70
,
PDBj:5t70
PDBsum
5t70
PubMed
28218747
UniProt
P01889
|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)
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