Structure of PDB 5t5m Chain A Binding Site BS01

Receptor Information
>5t5m Chain A (length=569) Species: 145261 (Methanothermobacter wolfeii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEYIIKNGFVYCPLNGVDGEKMDICVKDGKIVESVSDSAKVIDASGKIVM
PGGVDPHSHIAGAKVNVGRMYRPEDSKRDAEKFKGGRAGSGFSVPSTFMT
GYRYAQMGYTTAMEAAMPPLLARHTHEEFHDTPIIDHAAYPLFGNNWFVM
EYLKEGDVDACAAYASWLLRATKGYTIKIVNPAGTEAWGWGGNVHGIYDP
APYFDITPAEIIKGLAEVNEKLQLPHSIHLHCNDLGHPGNYETTLASFDV
PKNIKPNPATGSRDTVLYATHVQFHSYGGTTWRDFVSEAPKIADYVNKND
HIVIDVGQITLDETTTMTADGPMEYDLHSLNGLKWANCDVELETGSGVVP
FIYSARAPVPAVQWAIGMELFLLIDNPEKVCLTTDSPNAGPFTRYPRVIA
WLMSNKYRMNLIEGELHKWAQRKSTVATIDREYTFSEIAQITRATSAKVL
GLSDTKGHLGVGADADIAVYDINPETVDPSAEYMAIEEAFSRAACVLKDG
EIVVKDGEVVASPHGRTYWVDTQVDESIYSEVLANVESKFKQYYSVNFAN
YPVQDDYLPKSAPVKGVML
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5t5m Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5t5m The methanogenic CO2 reducing-and-fixing enzyme is bifunctional and contains 46 [4Fe-4S] clusters.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		K178 H231 H271
Binding residue
(residue number reindexed from 1)		K178 H231 H271
Annotation score4
Enzymatic activity
Enzyme Commision number 1.2.99.5: Transferred entry: 1.2.7.12.
Gene Ontology
Molecular Function
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5t5m, PDBe:5t5m, PDBj:5t5m
PDBsum5t5m
PubMed27846502
UniProtO74030

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