Structure of PDB 5t1z Chain A Binding Site BS01

Receptor Information
>5t1z Chain A (length=240) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLEMAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLL
ILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5t1z Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.
Resolution2.102 Å
Binding residue
(original residue number in PDB)		I358 K362 L372 V376 E380 D538 E542 M543
Binding residue
(residue number reindexed from 1)		I54 K58 L68 V72 E76 D229 E233 M234
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5t1z, PDBe:5t1z, PDBj:5t1z
PDBsum5t1z
PubMed29739819
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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